abiraterone acetate tablets, 250 mg film-coated tablets,500 mg film-coated tablets, prostate cancer treatment, Abirataj Taj pharma

Abiraterone Acetate Tablets

Abirataj is indicated in combination with prednisone for the treatment of patients with
• Metastatic castration-resistant prostate cancer (CRPC)
• Metastatic high-risk castration-sensitive prostate cancer (CSPC)

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Abirataj Tablets

Abiraterone Acetate Tablets 250mg for prostate cancer

Abirataj­ is a prescription medicine that is used along with prednisone. Abirataj is used to treat men with prostate cancer that has spread to other parts of the body. Abirataj­ is not for use in women. Abiraterone acetate (Abirataj)­ is converted in vivo to abiraterone, an androgen biosynthesis inhibitor, that inhibits 17 α‑hydroxylase/C17,20-lyase (CYP17). This enzyme is expressed in testicular, adrenal, and prostatic tumor tissues and is required for androgen biosynthesis. CYP17 catalyzes two sequential reactions: 1) the conversion of pregnenolone and progesterone to their 17α-hydroxy derivatives by 17α-hydroxylase activity and 2) the subsequent formation of dehydroepiandrosterone (DHEA) and andro­ stenedione, respectively, by C17, 20 lyase activity. DHEA and androstenedione are androgens and are precursors of testosterone. Inhibition of CYP17 by abiraterone can also result in increased mineralocorticoid production by the adrenals. Androgen sensitive prostatic carcinoma responds to treatment that decreases androgen levels. Androgen deprivation therapies, such as treatment with GnRH agonists or orchiectomy, decrease androgen production in the testes but do not affect androgen production by the adrenals or in the tumor. ­Abirataj decreased serum testosterone and other androgens in patients in the placebo‑controlled clinical trial. It is not necessary to monitor the effect of Abirataj­ on serum testosterone levels. Changes in serum prostate specific antigen (PSA) levels may be observed but have not been shown to correlate with clinical benefit in individual patients.

Abirataj (Abiraterone Acetate) Tablets

Abirataj (abiraterone acetate) is indicated in combination with prednisone for the treatment of patients with
• Metastatic castration-resistant prostate cancer (CRPC)
• Metastatic high-risk castration-sensitive prostate cancer (CSPC)

Get Started
Abirataj (abiraterone acetate) Tabletsabiraterone acetate tablets, 250 mg film-coated tablets,500 mg film-coated tablets, prostate cancer treatment, Abirataj Taj pharma

Indications

Abirataj is indicated in combination with prednisone for the treatment of patients with • Metastatic castration-resistant prostate cancer (CRPC) • Metastatic high-risk castration-sensitive prostate cancer (CSPC)

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Dosage

Recommended Dose For Metastatic CRPC
The recommended dose of abirataj is 1,000 mg (two 500 mg tablets or four 250 mg tablets) orally once daily with prednisone 5 mg orally twice daily.

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Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.. Stop taking Abiraterone Acetate Tablet and see a doctor immediately if you notice any of the following side effects.

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Drug Interactions

Drugs That Inhibit Or Induce CYP3A4 Enzymes
In a dedicated drug interaction trial, co-administration of rifampin, a strong CYP3A4 inducer, decreased exposure of abiraterone by 55%.

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Precautions

Abirataj may cause hypertension, hypokalemia, and fluid retention increased mineralocorticoid levels resulting from CYP17 inhibition.Monitor patients for hypertension, hypokalemia, and fluid retention at least once a month.

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Pharmacology

Mechanism Of Action
Abiraterone acetate (Abirataj) is converted in vivo to abiraterone, an androgen biosynthesis inhibitor, that inhibits 17 α-hydroxylase/C17,20-lyase (CYP17).

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Patient Counseling Information

PATIENT COUNSELING INFORMATION DOWNLOAD Abirataj (abiraterone acetate) Tabletsabiraterone acetate tablets, 250 mg film-coated tablets,500 mg film-coated tablets, prostate cancer treatment, Abirataj Taj pharma

Advise the patient to read the FDA-approved patient labeling
Hypertension, Hypokalemia, and Fluid Retention
Adrenocortical Insufficiency.

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Our Products

Abirataj tablets are available in 500 mg film-coated tablets, 250 mg film-coated tablets and 250 mg uncoated tablets with the following inactive ingredients.

Abirataj (abiraterone acetate) Tabletsabiraterone acetate tablets, 250 mg film-coated tablets,500 mg film-coated tablets, prostate cancer treatment, Abirataj Taj pharma
Abirataj 250mg Tablets

Abiraterone Acetate Tablets is an androgen biosynthesis inhibitor which comes under the strength of 250 mg in each tablet.

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Abirataj (abiraterone acetate) Tabletsabiraterone acetate tablets, 250 mg film-coated tablets,500 mg film-coated tablets, prostate cancer treatment, Abirataj Taj pharma
Abirataj 500mg Tablets

Each film-coated tablet contains 500 mg of abiraterone acetate.Excipients with known effect.Each film-coated tablet contains 253.2 mg of lactose and 13.5 mg.

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Full Prescribing Information Contents

FULL PRESCRIBING INFORMATION CONTENTS DOWNLOAD Abirataj (abiraterone acetate) Tabletsabiraterone acetate tablets, 250 mg film-coated tablets,500 mg film-coated tablets, prostate cancer treatment, Abirataj Taj pharma

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292

Patient benefired from generics

30

Percent off cost the brand medicine

65

Hospital and leading oncology care

16

Continuous off Low Income Options